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Prioritizing quality improvement for the treatment of psychiatric disturbances following traumatic brain injury
Investigator (PI): Albrecht, Jennifer S
Performing Organization (PO): (Current): University of Maryland, School of Medicine, Department of Epidemiology and Public Health / (410) 706-3491
Supporting Agency (SA): Agency for Healthcare Research and Quality (AHRQ)
Initial Year: 2016
Final Year: 2021
Record Source/Award ID: RePorter/K01HS024560
Funding: 2016 Award Amount: $144,413
Award Type: Grant
Abstract: This K01 application is designed to prepare the applicant for a successful, independently funded research career applying methods of stakeholder engagement to investigate the epidemiology of trauma, specifically psychiatric disturbances following TBI. Psychiatric disturbances such as depression, anxiety, and post-traumatic stress disorder (PTSD) following traumatic brain injury (TBI) are associated with poorer cognitive and functional recovery and efficacious treatment would likely improve outcomes. The long-term goal of the proposed research is to advance the conduct of patient-centered outcomes research on treatment for psychiatric disturbances following TBI to improve the quality of care. The primary objective of this application is to prioritize patient-selected strategies to overcome barriers to receipt of treatment for psychiatric disturbances following TBI. The specific aims are 1) assess patient-centered barriers and facilitators of treatments across comparator treatments and patient groups, 2) evaluate current treatment patterns and comparative safety associated with treatment of psychiatric disturbances following TBI, and 3) prioritize patient-selected strategies to overcome barriers to the receipt of treatment for specific comparator treatments and populations. Two approaches will be employed to identify barriers and facilitators of the receipt of treatment for the three most common psychiatric disturbances following TBI (depression, anxiety, and PTSD). I will implement training in methods of patient engagement and work with my PCOR advisory committee and mentors to identify and recruit patient partners, including individuals with TBI, their family members, and healthcare providers. We will use focus groups and interviews to assess patient-centered barriers and facilitators of treatments across comparator treatments and patient groups and identify comparator treatments for psychiatric disturbances for comparative safety analyses. Next, I will quantify disparities in treatment patterns associated with the three most common psychiatric disturbances following TBI and perform comparative safety analyses to identify variation of treatment risk among defined subgroups. Finally, I will work with my PCOR advisory committee to prioritize patient-selected strategies to overcome barriers to the receipt of treatment for psychiatric disturbances following TBI. The proposed research employs the best of qualitative and quantitative approaches to assess the treatment of psychiatric disturbances following TBI. Patients with TBI will form part of a research advisory committee that will be actively engaged throughout the research process and will drive research questions. The significance of this research is that it will improve the quality of care for patients with psychiatric disturbances following TBI by prioritizing patient-selected strategies to overcome barriers to the receipt of treatment, and by providing needed information on treatment patterns and safety of current pharmacologic treatments.
MeSH Terms:
  • Anxiety /complications
  • /therapy
  • Brain Injuries /*complications
  • /*psychology
  • Cognition
  • Depression /complications
  • /therapy
  • Health Services Accessibility
  • Humans
  • Mental Disorders /*complications
  • /epidemiology /*therapy
  • Mental Health Services /organization & administration
  • /*standards
  • Outcome Assessment, Health Care
  • Patient Safety
  • Patient-Centered Care
  • Quality Improvement
  • Quality of Health Care
  • Risk
  • Stress Disorders, Post-Traumatic /complications
  • /therapy
Country: United States
State: Maryland
Zip Code: 21201
UI: 20163002
Project Status: Completed