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| SIREN--CORE-EM (COalition for REsearch in Emergency Medicine) hub alliance | |
|---|---|
| Investigator (PI): | Wright, David W; Cairns, Charles B; Jones, Elizabeth B; Merck, Lisa H; Papa, Linda; Selker, Harry P |
| Performing Organization (PO): |
(Current): Emory University, School of Medicine, Department of Emergency Medicine / (404) 778-5975 |
| Supporting Agency (SA): | National Institutes of Health (NIH), National Institute of Neurological Disorders and Stroke (NINDS) |
| Initial Year: | 2017 |
| Final Year: | 2022 |
| Record Source/Award ID: | RePorter/U24NS100673 |
| Funding: | 2017 Award Amount: $252,798 2018 Award Amount: $145,949 |
| Award Type: | Grant |
| Abstract: | The CORE-EM Alliance (COalition for REsearch in Emergency Medicine) brings to SIREN (Strategies to Innovate EmeRgENcy Care Clinical Trials Network) six highly experienced research infrastructures, each with their own 5 spokes, partnering to create an innovative single super hub in the 10-hub SIREN network. The goal of CORE-EM is to provide a highly functioning infrastructure for rapid implementation and high-quality performance of large pragmatic clinical trials for a wide variety of emergency conditions, including, neurology, cardiovascular, respiratory, hematologic, and trauma-related emergencies. Our model is remarkably flexible and efficient, as we can be as lean as six independent sites or have the ability to rapidly expand to 30-plus enrolling sites. The CORE-EM leverages veteran leadership and experienced research teams with a long history of prior successful collaboration and exemplary clinical trial performance and provides SIREN access to an impressively diverse patient population, spanning large geographic regions within the southern and eastern United States. The CORE-EM Alliance will easily be capable of implementing four or more simultaneous large (>1,000 patient), simple, pragmatic trials in the emergency department (ED) and out-of-hospital settings. CORE-EM is committed to be an extraordinary partner for SIREN with a focus on conducting rigorous trials and assessments of novel therapeutic interventions in an aim to improve the lives of our patients. |
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| Country: | United States |
| State: | Georgia |
| Zip Code: | 30322 |
| UI: | 20184385 |
| Project Status: | Ongoing |