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Information about ongoing health services research and public health projects
| Comparison of treatment efficacy for prostate cancer.
(Archived Project) |
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|---|---|
| Investigator (PI): | Albertsen, Peter C |
| Performing Organization (PO): |
(Current): University of Connecticut Health Center |
| Supporting Agency (SA): | Agency for Healthcare Research and Quality (AHRQ) |
| Initial Year: | 1998 |
| Final Year: | 2003 |
| Record Source/Award ID: | CRISP/R01HS09578 |
| Award Type: | Grant |
| Abstract: | This is a prospective cohort study of men diagnosed during the early 1990's with prostate carcinoma in the state of Connecticut. The study is primarily descriptive using the Connecticut tumor registry. The investigators propose to determine frequencies and timing of secondary cancer therapies among men treated in this community-cohort. They will also determine the frequency and timing of PSA elevation as a reflection of an increasing tumor burden. Ten year cause-specific and all-cause mortality will be determined. Initial tumor histology slides will be retrieved and reviewed by an experienced pathologist. Specific questions to be addressed will include: outcomes among specific treatment groups including surgery, radiation or conservative treatment. These will be stratified by controlling for age, race, pre-treatment PSA, surgical stage and commodity. Other questions include the risk of receiving secondary cancer therapy controlling for these initial issues. Finally, they will determine the ability of demographic, co-morbidity, histologic grade, and pre-treatment PSA to predict disease progression and mortality. |
| MeSH Terms: |
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| Keywords: |
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| Country: | United States |
| State: | Connecticut |
| Zip Code: | 06030 |
| UI: | 98300050 |
| Project Status: | Archived |